対象遺伝子リスト
| 検査項目 | 対象遺伝子 |
|---|---|
| Axen™ MGPT Standard (56 遺伝子) |
APC, ATM, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, DICER1, EPCAM, FH, FLCN, GALNT12, GREM1, HOXB13, MAX, MEN1, MET, MLH1, MSH2, MSH3, MSH6, MUTYH, NF1, NF2, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, RB1, RET, RNF43, RPS20, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, STK11, TMEM127, TP53, TSC1, TSC2, VHL, WT1 |
| Axen™ MGPT Master (114 遺伝子) |
ABRAXAS1, AIP, ALK, APC, APOBEC3A, APOBEC3B, APOBEC3G, ATM, ATR, AXIN2, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDH23, CDK4, CDKN1C, CDKN2A, CHEK2, DDB1, DDB2, DICER1, EGFR, EPCAM, ERBB2, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, FANCC, FANCM, FH, FLCN, GALNT12, GEN1, GJB1, GJB2, GPR101, GREM1, HOXB13, MAX, MEN1, MET, MFN2, MITF, MLH1, MLH3, MPZ, MRE11, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NTHL1, PALB2, PBRM1, PHOX2B, PMP22, PMS2, POLD1, POLE, POLH, POT1, POU3F4, PRKAR1A, PRPF31, PRPH2, PRSS1, PTCH1, PTEN,RAD50, RAD51B, RAD51C, RAD51D, RB1, RECQL, RET, RHO, RINT1, RNF43, RP1, RPGR, RPS20, SCG5, SDHA, SDHAF2, SDHB, SDHC, SDHD, SLC26A4, SMAD4, SMARCA4, SMARCB1, STK11, SUFU, TECTA, TMEM127, TP53, TSC1, TSC2, USH2A, VHL, WT1, XPA, XPC |
| Axen™ MGPT Specific X-01 Brain & nerves 脳・神経 (28遺伝子) |
APC, BAP1, BRCA1, BRCA2, CDKN2A, EPCAM, MAX, MEN1, MLH1, MSH2, MSH6, NBN, NF1, NF2,PALB2, PMS2, PTEN, RB1, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, TP53, TSC1, TSC2, VHL |
| Axen™ MGPT Specific X-02 Pituitary gland 下垂体 (4遺伝子) |
AIP, CDH23, GPR101, MEN1 |
| Axen™ MGPT Specific X-03 Eye 眼 (11遺伝子) |
BAP1, EPCAM, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TSC1, TSC2, VHL |
| Axen™ MGPT Specific X-04 Thyroid & parathyroids 甲状腺、副甲状腺 (5遺伝子) |
APC, DICER1, MEN1, PTEN, RET |
| Axen™ MGPT Specific X-05 Mammary glands乳腺 (14遺伝子) |
ATM, BARD1, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, NF1, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53 |
| Axen™ MGPT Specific X-06 Lungs 肺 (11遺伝子) |
CDK4, CDKN2A, DICER1, EGFR, FLCN, HER2, SMAD4, STK11, TP53, TSC1, TSC2 |
| Axen™ MGPT Specific X-07 Stomach & duodenum 胃・十二指腸(16遺伝子) |
APC, ATM, BMPR1A, BRCA1, BRCA2, CDH1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, SMAD4, STK11, TP53 |
| Axen™ MGPT Specific X-08 Pancreas 膵臓(14遺伝子) |
ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MEN1, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, STK11, VHL |
| Axen™ MGPT Specific X-09 Biliary tract 胆道(10遺伝子) |
APC, BRCA1, BRCA2, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11 |
| Axen™ MGPT Specific X-10 Large intestine 大腸(25遺伝子) |
APC, AXIN2, BLM, BMPR1A, CHEK2, EPCAM, FLCN, GALNT12, GREM1, MLH1, MLH3, MSH2, MSH3, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, RNF43, RPS20, SMAD4, STK11, TP53 |
| Axen™ MGPT Specific X-11 Kidneys 腎臓(20遺伝子) |
BAP1, CHEK2, DICER1, EPCAM, FH, FLCN, MET, MLH1, MSH2, MSH6, PBRM1, PMS2, PTEN, SDHB, SDHC, SDHD, TSC1, TSC2, VHL, WT1 |
| Axen™ MGPT Specific X-12 Adrenal glands 副腎(11遺伝子) |
MAX, MEN1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, TMEM127, TP53, VHL |
| Axen™ MGPT Specific X-13 Upper urinary tract 上部尿路(5遺伝子) |
EPCAM, MLH1, MSH2, MSH6, PMS2 |
| Axen™ MGPT Specific X-14 Prostate 前立腺(19遺伝子) |
ABRAXAS1, ATM, ATR, BRCA1, BRCA2, BRIP1, CHEK2, EPCAM, GEN1, HOXB13, MLH1, MRE11, MSH2, MSH6, NBN, PALB2, PMS2, RAD51C, RAD51D |
| Axen™ MGPT Specific X-15 Cervix 子宮頚部(2遺伝子) |
DICER1, STK11 Axen™ MGPT Specific X-16 Uterus 子宮 |
| Axen™ MGPT Specific X-16 Uterus 子宮体部(11遺伝子) |
EPCAM, MLH1, MSH2, MSH6, MUTYH, NTHL1, PMS2, POLD1, POLE, PTEN, STK11 |
| Axen™ MGPT Specific X-17 Ovaries, fallopian-tubes & peritoneum 卵巣・卵管・腹膜(14遺伝子) |
ATM, BRCA1, BRCA2, BRIP1, DICER1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, RAD51C, RAD51D, STK11 |
| Axen™ MGPT Specific X-18 Skin 皮膚(21遺伝子) |
CDK4, CDKN2A, DDB1, DDB2, EPCAM, ERCC2, ERCC3, ERCC4, ERCC5, FH, MLH1, MSH2, MSH6, PMS2, POLH, PTCH1, PTEN, SUFU, TP53, XPA, XPC |
| Axen™ MGPT Specific X-19 Bone & soft tissue tumors 骨軟部腫瘍(19遺伝子) |
APC, DICER1, EPCAM, EXT1, EXT2, FH, MLH1, MSH2, MSH6, NF1, NF2, PMS2, RB1, SDHB, SDHC, SDHD, TP53, TSC1, TSC2 |
| Axen™ MGPT Specific X-20 Pediatrics cancers 小児(28遺伝子) |
APC, ATM, BLM, BMPR1A, CDKN1C, DICER1, MAX, MEN1, MLH1, MSH2, MSH6, MUTYH, NBN, NF1, PMS2, RB1, RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, SMAD4, STK11, TMEM127, TP53, VHL, WT1 対象遺伝子リスト 分類 |
遺伝性腫瘍にかかる検査 取り扱い検査一覧
| 分類 | 検査項目 | 備考 | 対象遺伝子数/サイト数 |
|---|---|---|---|
| MGPT | Axen™ MGPT Standard | 56遺伝子 | |
| MGPT | Axen™ MGPT Master | 114遺伝子 | |
| MGPT | Axen™ MGPT Specific X-01 | (Brain & nerves / 脳・神経) | 28遺伝子 |
| MGPT | Axen™ MGPT Specific X-02 | (Pituitary gland / 下垂体) | 4遺伝子 |
| MGPT | Axen™ MGPT Specific X-03 | (Eye / 眼) | 11遺伝子 |
| MGPT | Axen™ MGPT Specific X-04 | (Thyroid & parathyroids / 甲状腺、副甲状腺) | 5遺伝子 |
| 14遺伝子 | Axen™ MGPT Specific X-05 | (Mammary glands / 乳腺) | 14遺伝子 |
| MGPT | Axen™ MGPT Specific X-06 | (Lungs / 肺) | 11遺伝子 |
| MGPT | Axen™ MGPT Specific X-07 | (Stomach & duodenum / 胃・十二指腸) | 16遺伝子 |
| MGPT | Axen™ MGPT Specific X-08 | (Pancreas / 膵臓) | 14遺伝子 |
| MGPT | Axen™ MGPT Specific X-09 | (Biliary tract / 胆道) | 10遺伝子 |
| MGPT | Axen™ MGPT Specific X-10 | (Large intestine / 大腸) | 25遺伝子 |
| MGPT | Axen™ MGPT Specific X-11 | (Kidneys / 腎臓) | 20遺伝子 |
| MGPT | Axen™ MGPT Specific X-12 | (Adrenal glands / 副腎) | 11遺伝子 |
| MGPT | Axen™ MGPT Specific X-13 | (Upper urinary tract / 上部尿路) | 5遺伝子 |
| MGPT | Axen™ MGPT Specific X-14 | (Prostate / 前立腺) | 19遺伝子 |
| MGPT | Axen™ MGPT Specific X-15 | (Cervix / 子宮頚部) | 2遺伝子 |
| MGPT | Axen™ MGPT Specific X-16 | (Uterus / 子宮体部) | 11遺伝子 |
| MGPT | Axen™ MGPT Specific X-17 | (Ovaries, fallopian tubes & peritoneum / 卵巣・卵管・腹膜) | 14遺伝子 |
| MGPT | Axen™ MGPT Specific X-18 | (Skin / 皮膚) | 21遺伝子 |
| MGPT | Axen™ MGPT Specific X-19 | (Bone & soft tissue tumors / 骨軟部腫瘍) | 19遺伝子 |
| MGPT | Axen™ MGPT Specific X-20 | (Pediatrics cancers / 小児) | 28遺伝子 |
| 単一遺伝子検査 | Axen™ BRCA1/2 | 2遺伝子 | |
| MLPA法検査 | MLPA for BRCA1/2 | 2遺伝子 | |
| MLPA法検査 | MLPA (BRCA1) | 1遺伝子 | |
| MLPA法検査 | MLPA (BRCA2) | 1遺伝子 | |
| MLPA法検査 | MLPA (BRCA1/2以外) | 1遺伝子 | |
| シングルサイト検査 | シングルサイト検査 (BRCA1/2) | 1遺伝子 | |
| シングルサイト検査 | シングルサイト検査 (BRCA1/2以外) | 1遺伝子 |
